Publications

• Yulin Mo, Alexander, F. A. Keszei, Shagun Kothari, Heyi Liu, Anni Pan, Paige Kim, Jiachuan Bu, Albert Kamanzi, David L. Dai, Mohammad T. Mazhab-Jafari, Juan Chen, Sabrina Leslie and Gang Zheng. “Lipid-siRNA Organization Modulates the Intracellular Dynamics of Lipid Nanoparticles”.  Journal of the American Chemical Society (2025) https://doi.org/10.1021/jacs.4c18308
  
  
• Albert Kamanzi, Yao Zhang, Yifei Gu, Faith Liu, Romain Berti, Benjamin Wang, Fariba Saadati, Marco A. Ciufolini, Jayesh Kulkarni, Pieter Cullis, and Sabrina Leslie. “Quantitative Visualization of Lipid Nanoparticle Fusion as a Function of Formulation and Process Parameters.” ACS Nano 2024 18 (28), 18191-18201 https://doi.org/10.1021/acsnano.3c12981

• C. Shaheen, C. Hastie, K. Metera, S. Scott, Z. Zhang, S. Chen, G. Gu, L. Weber, B. Munsky, D. Levens, C. Benham, and S. R. Leslie. “Non-equilibrium structural dynamics of supercoiled DNA plasmids exhibit asymmetrical relaxation.” Nucleic Acids Research (2022), 50(5): 2754-2764. https://doi.org/10.1093/nar/gkac101

• A. Kamanzi, Y. Gu, R. Tahvildari, Z. Friedenberger, X. Zhu, R. Berti, M. Kurylowicz, D. Witzigmann, J. Kulkarni, J. Leung, John Andersson, Andreas Dahlin, Fredrik Hook, Mark Sutton, Pieter R. Cullis, and S. R. Leslie. “Simultaneous, single-particle measurements of size and loading give new insights into the structure of drug-delivery nanoparticles.” ACS Nano (2021), 15, 12, 19244-19255. https://doi.org/10.1021/acsnano.1c04862

• S. R. Leslie, et. al. “Single-molecule imaging of the biophysics of molecular interactions in cell-like conditions, without tethers, and with precision and control.” Current Opinion in Biomedical Engineering (2019) 12: 75-82. https://doi.org/10.1016/j.cobme.2019.10.004

• S. Scott, C. Shaheen, B. McGuiness, K. Metera, F. Kouzine, D. Levens, C. J. Benham, S. R. Leslie. “Single-molecule visualization of the effects of ionic strength and crowding on structure-mediated interactions in supercoiled DNA molecules.” Nucleic Acids Research (2019), 47, 12, 6360-6368. https://doi.org/10.1093/nar/gkz408

• M. Shayegan, R. Tahvildari, L. Kisley, K. Metera, S. W. Michnick, S. R. Leslie. “Probing inhomogeneous diffusion in the microenvironments of phase-separated polymers under confinement”. Journal of the American Chemical Society. (2019), 141, 19, 7751-7757. https://doi.org/10.1021/jacs.8b13349

• K. Thiombane, N. Coutin, D. J. Berard, R. Tahvildari, S. R. Leslie, C. Nislow. “Single-cell analysis for drug development using Convex Lens-Induced Confinement (CLiC) imaging.” BioTechniques (2019) 67(5): 210-217. https://doi.org/10.2144/btn-2019-0067

• D. J. Berard, S.R. Leslie. “Miniaturized flow cell with pneumatically-actuated vertical nanoconfinement for single-molecule imaging and manipulation.” Biomicrofluidics (2018), 12, 054107. https://doi.org/10.1063/1.5052005

• S. Scott, et. al. “Visualizing structure-mediated interactions in supercoiled DNA molecules” Nucleic Acids Research. (2018), 10, 1093. https://doi.org/10.1093/nar/gky266

• T. Shendruk, D. Sean, D. Berard, J. Wolf, J. Dragoman, S. Battat, G. Slater, S. R. Leslie. “Rotation-induced Macromolecular Spooling DNA” Physical Review X 7, (2017), 031005(1-11).
  https://doi.org/10.48550/arXiv.1706.01861

• D. Berard, M. Shayegan, F. Michaud, G. Henkin, S. Scott, S. R. Leslie. “Formatting and Ligating Biopolymers using Adjustable Nanoconfinement”. Applied Physics Letters (2016), 109, 033702. https://doi.org/10.1063/1.4958196

• G. Henkin, D. Berard, F. Stabile, M. Shayegan, J. S. Leith, S. R. Leslie. “Manipulating and visualizing molecular interactions in customized nanoscale spaces”. Analytical Chemistry (2016) 88(22), 11100-11107. https://doi.org/10.1021/acs.analchem.6b03149

• J. S. Leith, A. Kamanzi, D. Sean, D. Berard, A. Guthrie, C.M.J. McFaul, G. Slater, H. de Haan, S. R. Leslie. “Free energy of a polymer in slit-like confinement from the Odijk to the bulk regime”. Macromolecules (2016), 49 (23) 9266-9271. https://doi.org/10.1021/acs.macromol.6b01805

• B. Jia, T.L. Wee, D. Berard, A. Mallik, D. Juncker, C. M. Brown, S. R. Leslie. “Parallelized Cytoindentation Using Convex Micropatterned Surfaces”. Biotechniques (2016), 61, (2), 73-82. https://doi.org/10.2144/000114436

• J. Ahamed, S. Mahshid, D. Berard, F. Michaud, R. Sladek, W. Reisner, S. R. Leslie. “Continuous Confinement Fluidics: Getting Lots of Molecules in Small Spaces”. Macromolecules (2015), 49, (7) 2853-2859. https://doi.org/10.1021/acs.macromol.5b02617

• S. Mahshid, M. J. Ahamed, D. Berard, S. Amin, R. Sladek, S. R. Leslie, W. Reisner. “Development of a Platform for Single-Cell Genomics Using Convex Lens-Induced Confinement”. Lab on a Chip (2015), 15, 3013-3020. https://doi.org/10.1039/C5LC00492F

• A. Arsenault, J. S. Leith, G. Henkin, C. McFaul, M. Tarling, R. Talbot, D. Berard, F. Michaud, S. Scott, S. R. Leslie. “Open-frame System for Single–Molecule Microscopy”. Review of Scientific Instruments (2015), 86 (3), 033701. https://doi.org/10.1063/1.4913271

• D. Berard, F. Michaud, S. Mahshid, M. J. Ahamed, C. McFaul, J. S. Leith, P. Berube, R. Sladek, W. Reisner, S. R. Leslie. “Convex lens-induced nanoscale templating”. P.N.A.S. (2014), 111, 37. https://doi.org/10.1073/pnas.1321089111

• D. Berard, C. McFaul, J. S. Leith, A. Arsenault, F. Michaud, S. R. Leslie. “Precision Platform for Convex Lens-Induced Confinement Microscopy”. Review of Scientific Instruments (2013), 84, 103704. https://doi.org/10.1063/1.4822276

• M. W. Elting, S. R. Leslie, L. S. Churchman, J. Korlach, C. McFaul, J. S. Leith, M. J. Levene, A. E. Cohen, J. A. Spudich. “Single- molecule fluorescence imaging of processive myosin with enhanced background suppression using linear Zero Mode Waveguides (ZMW) and Convex Lens-induced Confinement (CLiC)”. Optics Express (2013), 21 (1), 1189-1202. https://doi.org/10.1364/OE.21.001189

• S. R. Leslie, A. P. Fields, A. E. Cohen. “Convex Lens-induced Confinement for Imaging Single Molecules”. Analytical Chemistry (2010) 82 (14), 6224-6229. https://doi.org/10.1021/ac101041s

• A. E. Cohen, A. P. Fields, J. H. Hou, S. R. Leslie, M. J. Shon. “In honor of W. E. Moerner: Confining molecules for single-molecule spectroscopy.” Israel Journal of Chemistry (2010) 49 (3-4), 275. https://doi.org/10.1560/IJC.49.3-4.275

• J. D. Sau, S.R. Leslie, M. L. Cohen, D.M. Stamper-Kurn. “Spin squeezing of high-spin, spatially extended quantum fields”. New Journal of Physics (2010) 12, 085011.
  https://doi.org/10.48550/arXiv.1005.0603

• M. Vengalattore, J. Guzman, S. R. Leslie, F. Serwane, and D. M. Stamper-Kurn. “Periodic spin textures in a degenerate F=187Rb spinor Bose gas.” Physical Review A (2010) 81, 053612. https://doi.org/10.48550/arXiv.0901.3800

• S. R. Leslie, J. Guzman, M. Vengalattore, J.D. Sau, M.L. Cohen, D.M. Stamper-Kurn. “Amplification of fluctuations in a spinor Bose Einstein condensate.” Physical Review A (2009) 79, 043631. https://doi.org/10.1103/PhysRevA.79.043631

• J. D. Sau, S.R. Leslie, D.M. Stamper-Kurn, M.L. Cohen. “Theory of domain formation in inhomogeneous ferromagnetic dipolar condensates.” Physical Review A (2009) 80, 023622. https://doi.org/10.1103/PhysRevA.80.023622

• M. Vengalattore, S.R. Leslie, J. Guzman, D.M. Stamper-Kurn. “Spontaneously modulated spin textures in a dipolar spinor Bose-Einstein condensate.” Physical Review Letters (2008) 100, 170403. https://doi.org/10.1103/PhysRevLett.100.170403

• M. Vengalattore, J. M. Higbie, S. R. Leslie, J. Guzman, L. E. Sadler, D. M. Stamper-Kurn. “High-resolution magnetometry with a spinor Bose-Einstein condensate.” Physical Review Letters (2007) 98, 200801. https://doi.org/10.1103/PhysRevLett.98.200801

• L. E. Sadler, J. M. Higbie, S. R. Leslie, M. Vengalattore, D. M. Stamper-Kurn. “Coherence-enhanced imaging of a degenerate Bose gas.” Physical Review Letters (2007) 98, 110401. https://doi.org/10.1103/PhysRevLett.98.110401

• L. E. Sadler, J. M. Higbie, S. R. Leslie, M. Vengalattore, D. M. Stamper-Kurn. “Spontaneous symmetry breaking in a quenched ferromagnetic spinor Bose condensate.” Nature (2006) 443, 312. https://doi.org/10.48550/arXiv.cond-mat/0605351

• J. M. Higbie, L. E. Sadler, S. Inouye, A. P. Chikkatur, S. R. Leslie, K. L. Moore, V. Savalli, D. M. Stamper-Kurn. “Direct, non-destructive imaging of magnetization in a spin-1 Bose gas.” Physical Review Letters (2005) 95, 050401. https://doi.org/10.1103/PhysRevLett.95.050401

• K. L. Moore, T. P. Purdy, K. W. Murch, S. Leslie, S. Gupta, and D. M. Stamper-Kurn. “Collimated, single-pass atom source from a pulsed alkali metal dispenser for laser-cooling experiments.” Review of Scientific Instruments (2005) 76, 023106. https://doi.org/10.1063/1.1841852

• S. Leslie, N. Shenvi, K. R. Brown, Dan M. Stamper-Kurn, and K. Birgitta Whaley. “Transmission spectrum of an optical cavity containing N atoms.” Physical Review A (2004) 69, 043805. https://doi.org/10.1103/PhysRevA.69.043805